产前空气污染暴露与儿童自闭症之间的关联:EPINED研究
Sharanpreet Kaur1,2, Paula Morales-Hidalgo1,2, Mònica Guxens3,4,5,6,7
1Nutrition and Mental Health Research Group (NUTRISAM), Universitat Rovira i Virgili (URV), Tarragona, Spain.
Journal of autism and developmental disorders
|November 20, 2025
概括
产前暴露于PM2.5和PM10等特定空气污染物的暴露与儿童患自闭症的可能性增加有关. 这项研究强调了空气质量对神经发育结果的影响.
科学领域:
- 环境健康 环境健康
- 神经发育障碍 神经发育障碍
- 儿科健康 儿科健康
背景情况:
- 空气污染越来越被认为是神经发育障碍的一个因素.
- 自闭症谱系障碍 (ASD) 风险可能受到关键发育时期环境暴露的影响.
研究的目的:
- 调查产前暴露于空气污染物和自闭症风险之间的关联.
- 在西班牙人口中检查与空气质量相关的自闭症症状和诊断病例.
主要方法:
- 查问卷 (CAST,EDUTEA) 对3727名儿童 (年龄在4岁至11岁) 的家长和教师进行了管理.
- 根据DSM-5标准对623名儿童进行个人评估,诊断为自闭症.
- 多重回归分析调整为共变量.
主要成果:
- 暴露于粗颗粒物 (PMcoarse),二氧化 (NO2) 和氧化 (NOx) 与更高的自闭症症状得分相关.
- 第二个三个月暴露于细颗粒物 (PM2.5) 和PM10与自闭症的可能性增加和自闭症特征的下值相关.
结论:
- 特定的空气污染物在关键怀孕和胎儿发育窗口期间构成潜在风险.
- 需要进一步的研究来了解空气污染物在儿童自闭症发病率上升中的作用.
相关概念视频
01:19Autism Spectrum Disorder
923
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
923
01:30Attention-Deficit/Hyperactivity Disorder
722
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
722
01:29Asthma-I: Introduction
3.3K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.3K