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Updated: Jan 10, 2026

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
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In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol

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对互白素-2的Treg反应的动力学和变化

Kumba Seddu1,2, Kaitavjeet Chowdhary1, Molly Henderson1

  • 1Department of Immunology, Harvard Medical School, Boston, MA 02115.

Proceedings of the National Academy of Sciences of the United States of America
|November 20, 2025
PubMed
概括

互白素-2 (IL2) 通过多种分子反应塑造T调节细胞 (Treg) 身份. 这项研究揭示了IL2信号变异如何塑造Treg异质性,影响它们的功能和稳态.

关键词:
在Treg细胞中.细胞因子 细胞因子免疫反应的免疫反应.

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