关于用于癌症生存分析的机器学习技术的系统审查
Autumn O'Donnell1,2, Michael Cronin3, Shirin Moghaddam2,4,5,6
1School of Mathematical and Statistical Sciences, University of Galway, Galway, Ireland.
Cancer medicine
|November 20, 2025
概括
机器学习 (ML) 显示了癌症存活率分析性能的改善. 多任务和深度学习方法看起来很有前途,但ML的实施在不同研究中存在很大差异.
科学领域:
- 在瘤学瘤学.
- 生物统计学 生物统计学
- 计算机科学 计算机科学
背景情况:
- 在癌症研究中,传统的生存分析存在局限性.
- 机器学习 (ML) 提供了潜在的解决方案,但性能不同.
- 关于ML对传统方法的持续优越性存在不确定性.
研究的目的:
- 系统地审查有关机器学习的文献,以分析癌症生存率.
- 评估不同ML方法的性能和可变性.
- 为了确定潜在的优越的ML策略,用于生存分析.
主要方法:
- 系统的文献审查遵循PRISMA指南.
- 使用关键词搜索电子数据库:机器学习,生存分析,癌症.
- 分析了最初包括的196项研究中的39项可比性研究.
主要成果:
- 机器学习在大多数癌症类型中显示出更好的预测性能.
- 不同ML方法的性能因癌症类型而异.
- 多任务和深度学习方法在一组研究中表现出卓越的表现.
- 观察到ML方法和实施的显著变化.
结论:
- 机器学习通常在癌症生存分析中提高预测性能.
- 虽然有希望,但多任务和深度学习方法需要进一步调查,因为报告有限.
- 为了进行可靠的比较,需要对ML方法和实施进行标准化.
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