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Updated: Jan 10, 2026

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis
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成熟的三级淋巴体结构支持B细胞介导的抗瘤免疫力,并且在直肠癌中被新辅助疗法破坏:一个多中心的回顾性研究

Na Tian1, Qianyu Wang2, Yuan Lv3

  • 1Senior Department of General Surgery, The First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, China; Beijing Chest Hospital, Capital Medical University, Beijing, 101149, China.

EBioMedicine
|November 20, 2025
PubMed
概括

在直肠癌中,成熟的三级淋巴体结构 (mTLS) 与更好的结局和B细胞活性有关. 新辅助疗法增加了T细胞,但减少了mTLS,这表明B细胞对非响应者的策略.

关键词:
新辅助疗法是一种新辅助疗法.这是直肠癌.三级淋巴状结构的第三级淋巴状结构.瘤的免疫微环境

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