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Updated: Jan 10, 2026

Detection of Mitochondria Membrane Potential to Study CLIC4 Knockdown-induced HN4 Cell Apoptosis In Vitro
13:20

Detection of Mitochondria Membrane Potential to Study CLIC4 Knockdown-induced HN4 Cell Apoptosis In Vitro

Published on: July 17, 2018

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氧化修饰G-四重复触发了CLIC4相关的线粒体功能障碍,促进了质母细胞瘤的进展

Xiaodong Li1, Yaning Fu1, Yalan Luo1

  • 1State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, China; Laboratory of Chemical Biology, School of Life Science and Technology, China Pharmaceutical University, Nanjing, Jiangsu, 211198, China; Department of Microbiology and Synthetic Biology, China Pharmaceutical University, Nanjing, Jiangsu, 211198, China.

Redox biology
|November 20, 2025
PubMed
概括

化物细胞内通道蛋白4 (CLIC4) 在质母细胞瘤中被上调,促进瘤生长和生存率低下. 沉默CLIC4通过维持氧化还原稳态来抑制质母细胞瘤的进展,提供了一个潜在的治疗点.

关键词:
在 CLIC4 中使用.DHX36 DHX36 的时间.在G-quadruplex中使用.质母细胞瘤 (glioblastoma) 是一个氧化应激是一种氧化应激.

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