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双甲基乙醇诱导的DNA甲基化异常可能会扰乱成年雄性斑马鱼的丸发育

Eui-Jin Lee1, Hyojin Lee2, Jiyun Kang3

  • 1Institute for Catholic Integrative Medicine, Incheon St. Mary's Hospital, The Catholic University of Korea, Incheon, Republic of Korea.

Environmental analysis, health and toxicology
|November 20, 2025
PubMed
概括

双甲基乙烯 (BADGE) 暴露会通过改变DNA甲基化来影响斑马鱼的雄性生殖. 这种表观遗传变化会影响胰岛素信号传递,并增加类固醇酶的表达,可能会破坏男性的生育能力.

关键词:
双甲二甲基基乙烯 (Bisphenol A diglycidyl ether) 是一种二聚乙烯的化合物.通过DNA甲基化.戈纳德·戈纳德 (Gonad Gonad) 是一个类固醇的产生.全基因组双硫酸盐测序斑马鱼是一种斑马鱼.

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