相关实验视频

Updated: Jan 10, 2026

Author Spotlight: AI-Driven Trypanosome Species Detection from Microscopic Images

Author Spotlight: AI-Driven Trypanosome Species Detection from Microscopic Images

Published on: October 27, 2023

大数据和人工智能:毒理学数字化转型的潜力和挑战

Donghyeon Kim¹, Jinhee Choi¹

¹School of Environmental Engineering, University of Seoul, Seoul, Republic of Korea.

Environmental analysis, health and toxicology

|November 20, 2025

概括

人工智能 (AI) 正通过启用预测模型来彻底改变毒理学和化学风险评估. 解决数据质量和模型透明度等挑战是监管接受和在安全科学中推进AI的关键.

科学领域:

计算毒理学和风险评估
科学研究中的人工智能
监管科学和化学安全

背景情况:

毒理学正在从观察转向预测科学,这是由计算进步和大数据推动的.
增加的计算能力和毒理学数据使化学风险评估使用人工智能 (AI) 的现代化成为可能.
人工智能为化学品优先级和安全评估提供了新的机会.

研究的目的:

探索当前的毒性数据库和人工智能方法 (机器学习,深度学习,大语言模型) 的现状.
检查案例研究,证明AI在毒性预测和化学物质优先级的应用.
确定挑战,并提出将人工智能整合到监管科学中的解决方案.

主要方法:

审查当前的毒性数据库和人工智能技术.
对使用人工智能用于毒性预测的代表性案例研究的分析.
讨论挑战,包括数据限制和模型可解释性.

主要成果:

人工智能,包括机器学习和深度学习,在毒性预测和化学品优先级方面显示出前景.
仍然存在重大挑战,特别是高质量的标准化数据集的稀缺性.
人工智能模型的"黑盒子"性质阻碍了监管机构的接受和信任.

结论:

可解释人工智能 (XAI) 和不利结果途径 (AOP) 框架对于提高模型解释性和监管接受度至关重要.
未来的研究应该专注于开发透明,可重复的AI模型,以进行可靠的化学安全评估.
推进人工智能作为新方法方法 (NAM) 对于下一代风险评估 (NGRA) 是必不可少的.

关键词:

人工智能的人工智能是人工智能.大数据就是大数据.新方法方法论新方法方法论下一代风险评估是什么毒性预测毒性预测

更多相关视频

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Published on: July 11, 2025

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods

Published on: June 6, 2025

相关概念视频

Issues And Trends In Healthcare Delivery System

Issues And Trends In Healthcare Delivery System

The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...

Types of Toxins

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...

MALDI-TOF Mass Spectrometry

MALDI-TOF Mass Spectrometry

Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...