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开放眼球损伤后同情性眼科医症的发病率和危险因素:基于人口的分析

Niloufar Bineshfar¹, Natalia Davila², Chloe Shields¹

¹From the Department of Ophthalmology (N.B., N.D., C.S., S.A.M., S.P., T.P., W.W.L.), Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.

American journal of ophthalmology

|November 20, 2025

概括

开放球损伤 (OGIs) 后的同情性眼病 (SO) 是罕见的,但是一个长期的风险. 早期的眼睛切除手术并没有显著降低SO风险,但某些种族面临更高的风险.

科学领域:

眼科医生眼科眼科
创伤外科手术创伤外科
公共卫生公共卫生

背景情况:

交感眼病 (SO) 是一种罕见但严重的疾病,可能发生在开放球损伤 (OGIs) 后.
了解SO的发病率,风险因素和潜在的预防措施对于患者的结果至关重要.

研究的目的:

为了确定OGI后的SO的发病率和风险因素.
评估早期眼睛切除手术 (核切除/内脏切除) 在预防SO的有效性.
确定与SO风险增加相关的人口因素.

主要方法:

使用TriNetX网络的非识别数据进行了回顾性临床队列研究.
在2004年9月至2024年9月期间,对63,763名被诊断患有OGI的患者进行了分析.
在受伤后的6个月,1,5年和10年计算SO发病率,使用Cox比例危险模型.

主要成果:

总体上,SO发生率在OGI后6个月为0.13%,在10年后为0.18%.
大多数SO病例 (74.3%) 在受伤6个月内出现.
在30天内提前去除眼睛显示了较低SO风险的非显著趋势 (HR0.655,P=.416).
增加SO风险与原住民夏威夷人/其他太平洋岛民 (HR:6.775) 和西班牙裔 (HR:2.862) 种族有关.

结论:

交感性眼病是一种罕见但在开放球损伤后存在的持续风险,主要在第一年内表现出来.
在30天内提前切除眼睛的手术没有显示出对SO的统计学上显著的保护作用.
建议针对夏威夷原住民/其他太平洋岛民和西班牙裔族群的个人进行有针对性的监测和随访,因为他们的SO风险较高.

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