在手术后被诊断患有癌症的患者中,进行手术前和手术内风险因素评估和预测中风风险的模型
Shangqi Chen1, Yuxuan Mo1, Xiangman Zeng2
1Department of Gastrointestinal and Hernia Ward, Ningbo No 2 Hospital, No.41 Xibei Street, Ningbo, Zhejiang, China.
概括
癌症手术显著增加了术后中风风险. 内手术性低血压 (IOH) 是癌症患者的独立预测因子,经过验证的名谱有助于风险预测.
科学领域:
- 神经外科 神经外科
- 在瘤学瘤学.
- 麻醉学 麻醉学
背景情况:
- 术后中风是一种严重并发症,死亡率高.
- 确定术后中风的预测因素对于患者的治疗结果至关重要.
- 术内低血压 (IOH) 在中风发展中的作用需要进一步研究.
研究的目的:
- 为了确定术后中风的预测因素.
- 调查手术内低血压和术后中风之间的关联,特别是在癌症患者中.
主要方法:
- 对574,102名接受非心血管,非神经外科手术的患者进行了回顾性分析.
- 后勤回归用于识别中风的独立风险因素.
- 开发和验证用于预测中风风险的诺莫格拉姆模型.
主要成果:
- 与癌症相关的手术与术后中风发生率增加67%有关.
- 癌症患者的独立预测因素包括年龄,中风史,心房动,功能衰竭,D-Dimer升高和持续的手术内低血压 (IOH).
- 诺米图表显示出强大的预测性能 (AUC为0.843和0.852).
结论:
- 癌症手术是术后中风的重要危险因素.
- 术内低血压是癌症患者中风的独立预测因子.
- 一个经过验证的脑电图有效地预测了手术后中风风险.
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