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Updated: Jan 10, 2026

Identification of Protein Interacting Partners Using Tandem Affinity Purification
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Identification of Protein Interacting Partners Using Tandem Affinity Purification

Published on: February 25, 2012

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选择性eIF4E-eIF4G配对和Trypanosomatids中的Cap-4识别机制:从EIF4E5-EIF4G1和EIF4E6-EIF4G5复合体的洞察

Renato Ferras Penteado1, Sophie Vichier-Guerre2, Beatriz Maria da Silva Pereira3

  • 1Carlos Chagas Institute, Oswaldo Cruz Foundation, Rua Prof. Algacyr Munhoz Mader, 3775, 81350-010 Curitiba, PR, Brazil.

Journal of molecular biology
|November 20, 2025
PubMed
概括

细胞的翻译启动在三子体中不同,使用独特的cap-4结构和多个eIF4E-eIF4G复合体. 晶体结构揭示了这些复杂物如何结合cap-4结构,解释了选择性相互作用.

关键词:
卡普-4绑定方式晶体结构 晶体结构eIF4E eIF4G 互动互动开始翻译 开始翻译试图使用松酸盐.

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