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在非裔男性中,非编码基因变异导致前列腺癌风险更高

Shan Li1, Kaniz Fatema2, Nidharshan Sundarraj3

  • 1Cancer Data Science Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Nature communications
|November 20, 2025
PubMed
概括

通过深度学习识别的新遗传变异可能改善前列腺癌 (PrCa) 风险预测,特别是在非洲血统的男性中. 这些单核酸多态 (SNP) 影响基因调节,并提供比目前的多基因风险得分更精确的评估.

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