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Updated: Jan 10, 2026

A Model to Simulate Clinically Relevant Hypoxia in Humans
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长时间的间歇性缺氧加速心血管衰老和死亡率:来自OSA小鼠模型的见解

Mohammad Badran1,2, Clementine Puech3, David Gozal4

  • 1Department of Pediatrics, University of Missouri, Columbia, MO, USA. mbadran@health.missouri.edu.

npj aging
|November 20, 2025
PubMed
概括

终身阻塞性睡眠呼吸暂停 (OSA) 加快心血管衰老. 慢性间歇性缺氧 (IH) 在小鼠导致更高的死亡率,血压和心脏功能受损,强调了早期OSA诊断的必要性.

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Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
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