目前吸烟者与OSA前吸烟者之间临床特征的差异:一个横截面研究
Zhifeng Chen1,2,3,4, Yulin Shang5, Binaya Wasti6
1Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital, Central South University, 139 Middle Renmin Road, Changsha, 410011, Hunan, China.
Scientific reports
|November 20, 2025
概括
在阻塞性睡眠呼吸暂停 (OSA) 患者中,戒烟与年龄较大,疾病持续时间较长和BMI较高有关. 解决这些因素可以改善OSA结果并帮助戒烟.
科学领域:
- 睡眠医学 睡眠医学
- 肺部病理学 肺部病理学
- 成 药物 药物 药物 药物
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 的患病率正在增加,吸烟是其中的一个关键因素.
- 关于在OSA患者群体中预测戒烟的研究是有限的.
- 了解影响戒烟的因素对于管理OSA和改善患者健康至关重要.
研究的目的:
- 在被诊断患有OSA的个体中确定与戒烟相关的临床因素.
- 为了比较现有吸烟者与OSA前吸烟者的特征.
- 探索戒烟因素和OSA严重程度之间的相互作用.
主要方法:
- 分析了504名成年OSA患者和吸烟者的队列.
- 数据包括人口统计,多睡眠学 (PSG) 结果和临床信息.
- 用物流和考克斯比例危险回归模型来确定戒烟预测因素和相互作用.
主要成果:
- 与目前吸烟者 (69.0%) 相比,前吸烟者 (31.0%) 年龄较大,OSA 持续时间较长,OSA 严重程度 (AHI,ODI),BMI 和包装年数较高.
- 戒烟与年龄,OSA持续时间,AHI,BMI和并发症正相关,但与最小氧和 (MSaO2) 负相关.
- 与戒烟相关的OSA严重程度与高尿血,代谢综合征,肥胖和缺口性心脏病发生有显著的相互作用.
结论:
- 年龄,OSA持续时间,严重程度 (AHI),BMI和并发症是与OSA患者戒烟相关的关键因素.
- 针对这些因素的干预措施可能会提高OSA的戒烟成功率.
- 解决已识别的戒烟因素可能可以预防OSA恶化并改善患者的整体结果.
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