在患有阻塞性尿路病症的小鼠中,腺素A2a受体对手伊斯特拉德菲林的双相作用

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Updated: Jan 10, 2026

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction
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A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction

Published on: July 18, 2025

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Emily S H Yeung1,2, Duc Tin Tran1, Sri Nagarjun Batchu1

  • 1Keenan Research Centre for Biomedical Science, St. Michael's Hospital, 6-151 61 Queen Street East, Toronto, ON, M5C 2T2, Canada.

Scientific reports
|November 20, 2025
PubMed
概括

重新利用帕金森病药物伊斯特拉德菲林治疗脏疾病显示出有前途. 晚期干预用伊斯特拉德菲林减弱纤维化,但早期干预增加了小鼠的死亡率.

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