动脉优化的4D流量MRI用于量化静脉鼻腔和大脑静脉中的流量和脉动性
Arvid Westlund1,2, Anders Wåhlin3,4,5, Jan Malm6
1Clinical Sciences, Neurosciences, Umeå University, Umeå, 90187, Sweden. arvid.westlund@umu.se.
Scientific reports
|November 20, 2025
概括
一个动脉优化的4D流动MRI (磁共振成像) 扫描可以有效地评估大脑静脉流和脉动性. 这种单一的获取方法为评估老年人静脉血液动力学提供了一种可行的方法.
科学领域:
- 医疗成像医学成像
- 神经成像是一种神经成像.
- 心血管成像 - 心血管成像
背景情况:
- 使用4D流MRI进行脑动脉和静脉流量评估,需要不同的速度编码 (VENC) 设置以获得最佳的速度与噪声比 (VNR).
- 对动脉优化的VENC设置可能会降低静脉测量中的VNR,需要进一步评估.
研究的目的:
- 为了比较大脑静脉流量和脉动性评估,使用高VENC (动脉适应) 和低VENC (静脉适应) 的4D流量MRI序列.
- 评估使用单一,动脉优化的4D流动MRI采集用于同时进行大脑动脉和静脉流动分析的可行性.
主要方法:
- 在36名老年志愿者 (79 ± 5岁) 中使用了3特斯拉4D流MRI序列.
- 高VENC (110厘米/秒) 和低VENC (40厘米/秒) 的设置进行了比较,以评估大脑静脉,鼻和内静脉的流量和脉动性指数 (PI).
主要成果:
- 高VENC获取可视化了几乎所有的静脉结构,平均流量差异很小,鼻腔 (R=0.90-0.99) 和皮层静脉 (R=0.93) 之间有很强的相关性.
- 脉动率指数 (PI) 显示出中度至强度的一致性,除了直弦弦. 静脉VENC收购显示在加伦静脉和 jugular 静脉中的异名.
结论:
- 优化动脉脑循环的VENC设置可用于研究脑静脉流和脉动性.
- 单个动脉优化的4D流动MRI采集可能能够快速评估大脑动脉和静脉流动,尽管特定静脉结构存在一些限制.
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