银胺化物是否比化漆更有效地预防前牙的牙?
1School of Clinical Dentistry, University of Sheffield, Sheffield, UK. l.timms@sheffield.ac.uk.
Evidence-based dentistry
|November 20, 2025
概括
银胺化物 (SDF) 比化漆 (NaF) 更有效地预防母牙的新腔. 这项随机试验在接受SDF治疗的儿童中发现了较少的新表面.
科学领域:
- 儿科牙科 儿科牙科
- 皮肤病学 皮肤病学 皮肤病学
- 临床试验 临床试验
背景情况:
- 牙损是幼儿中普遍存在的问题,特别影响母牙.
- 早期干预策略对于管理和预防儿科患者病进展至关重要.
研究的目的:
- 为了比较银二胺化物 (SDF) 与化漆 (NaF) 在预防新的虫的疗效.
- 评估SDF和NaF在3至4岁儿童前牙中的有效性.
主要方法:
- 一项随机对照试验,涉及香港幼儿园的730名3-4岁儿童.
- 参与者每六个月接受38%的SDF或5%的NaF.
- 主要结局:每名30个月的儿童平均新表面数量;治疗意图分析.
主要成果:
- 621名儿童 (85%) 在30个月后被分析.
- 与NaF组 (0.54 ± 1.50) 相比,SDF组显示的新病变较少 (0.35 ± 1.09).
- 在SDF和NaF之间的新皮肤表面的差异是统计学上显著的 (p=0.048).
结论:
- 银胺化物 (SDF) 在防止新的皮表面方面表现出优于化漆 (NaF) 的效果.
- SDF是一种更有效的牙预防策略,用于幼儿的前牙.
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