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Updated: Jan 10, 2026

Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix
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生物直角点击化学可视化人类单细胞衍生的树突细胞中的免疫原HLA-A2受限制的B型肝炎病毒表位

Thijmen P Mostert1, Amy L Kessler2, Robbie J Luijten2

  • 1Department of Chemical Biology & Immunology, Leiden Institute of Chemistry, Leiden University, Leiden, 2333 CC, The Netherlands.

Journal of immunology (Baltimore, Md. : 1950)
|November 21, 2025
PubMed
概括

生物对等化学可以跟踪治疗性疫苗,以改善抗原处理和呈现研究. 这种方法允许可视化路由和对人类的定量表位分析.

关键词:
抗原的处理和呈现方式.生物直角点击化学核心抗原 (HBcAg) 是一种乙型肝炎病毒 (HBV)主体组织相容性抗原 (MHC)

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Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
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