糖尿病酸性脂肪酸症的全球负担
Viswanathan Mohan1, Kenneth Lee2
1Madras Diabetes Research Foundation, ICMR Collaborating Centre of Excellence and Dr. Mohan's Diabetes Specialities Centre (IDF Centre of Excellence in Diabetes Care), Chennai, India.
Diabetes technology & therapeutics
|November 21, 2025
概括
糖尿病酸性酸症 (DKA) 是一种严重的糖尿病并发症. 新的连续双葡萄糖-子传感器可能会改善对那些有DKA风险的人的管理.
科学领域:
- 内分泌学 在内分泌学.
- 代谢障碍 代谢障碍 代谢障碍
- 糖尿病管理 糖尿病管理
背景情况:
- 糖尿病酸性脂肪酸症 (DKA) 是一种严重的医疗紧急情况,影响1型糖尿病 (T1D) 患者,每年成人发病率为4%-8%,儿童在诊断时高达80%.
- 在2型糖尿病人群中,DKA的发病率正在上升,特别是在使用-葡萄糖共运输体2抑制剂 (SGLT-2i) 的情况下,通常以正常葡萄糖水平呈现为euglycemic DKA (euDKA).
- 在各种糖尿病表型中,包括怀孕和容易发生症的糖尿病中,DKA是一个重大问题,突出了其广泛的临床相关性.
研究的目的:
- 为了提供一个全面的概述,糖尿病酸性糖尿病 (DKA) 的全球负担.
- 审查糖尿病管理中子监测技术的最新进展.
- 讨论糖尿病分类的复杂性和新的监测工具的潜力.
主要方法:
- 关于不同类型糖尿病的DKA发病率,危险因素和临床表现的文献综述.
- 对子监测的最新技术进步进行分析,包括连续传感.
- 探索这些进展对临床实践和糖尿病分类的影响.
主要成果:
- DKA仍然是一个主要问题,特别是在T1D中,但由于SGLT-2i的使用,其发病率在T2D中正在增加,通常具有像eudka.com这样的非典型表现.
- 新兴的子监测技术,包括连续的双葡萄糖-子传感器,为改善DKA的早期检测和管理提供了潜力.
- 连续双重葡萄糖-子传感器的开发为高风险DKA个体的积极临床管理提供了一个有希望的途径.
结论:
- 在多种表型的糖尿病护理中,DKA是一个关键的,不断变化的挑战.
- 子监测方面的进步,特别是连续双传感器,对于减轻DKA风险至关重要.
- 改善糖尿病分类的监测和理解是改善患者治疗结果和预防DKA的关键.
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