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功能性消化不良患者的执行功能表现较低
Shumin He1, Shu Zhang1, Lulu Zeng1
1Department of Gastroenterology, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, P. R. China.
Journal of clinical and experimental neuropsychology
|November 21, 2025
概括
与健康个体相比,功能性消化不良患者表现出执行功能 (EFs) 的受损,包括注意力和认知灵活性. 这些认知缺陷与FD的症状严重程度和疾病持续时间相关.
科学领域:
- 神经科学是一个神经科学.
- 胃肠病学 胃肠病学
- 心理学 心理学 心理学
背景情况:
- 执行功能 (EF) 对于认知控制至关重要.
- 大脑成像研究表明,EFs在功能性消化不良 (FD) 中受到影响.
- 了解FD中的EF对于患者管理至关重要.
研究的目的:
- 为了比较FD患者和健康对照 (HC) 之间的EF.
- 研究FD患者的EF和临床特征之间的关系.
主要方法:
- 43名FD患者和43名匹配的HC参与了这项研究.
- 使用Stroop色词测试 (SCWT),威斯康星州卡片排序测试 (WCST) 和数字跨度测试 (DST) 来评估EF.
- 抑郁和焦虑被测量使用汉密尔顿尺度;临床数据包括疾病持续时间和症状严重程度.
主要成果:
- 与HC相比,FD患者在SCWT,DST和WCST上的表现较差.
- 具体来说,FD患者的完成时间更长,数字跨度得分更低,认知测试中的错误更多.
- 在FD患者中较差的EF与早期和食后和疾病持续时间负相关.
结论:
- 患有FD的患者在执行功能方面表现出显著的缺陷.
- 这些认知障碍与功能性消化不良的持续时间和特定症状有关.
- 定位EF可能有利于管理FD.
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