献血者病史对输血相关感染风险的影响
Collince Odiwuor Ogolla1, Benard Guya1, Apollo O Maima2
1School of Public Health & Community Development, Maseno University, P.O. Box 3275-40100, Maseno, Kenya.
Global health, epidemiology and genomics
|November 21, 2025
概括
捐赠者病史,包括过去的捐赠和危险行为,显著影响了输血相关感染 (TRIs). 识别这些因素对于防止通过输血传染传染病的传播至关重要.
科学领域:
- 输血医学 输血医学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 输血相关感染 (TRIs) 尽管在查方面取得了进展,但仍构成重大国际风险.
- 输血仍然是传染病传播的潜在途径.
研究的目的:
- 为了确定与输血相关感染相关的捐赠者病史因素.
- 评估捐赠者的人口统计和行为对感染风险的影响.
主要方法:
- 这是一项涉及108名捐赠者的横截面研究.
- 分析捐赠者的医疗记录和查表格.
- 统计分析包括千平方测试和后勤回归.
主要成果:
- 13.9%的血液单位感染了输血传染性感染 (TTIs).
- 乙型肝炎 (4.6%),艾滋病毒 (3.7%) 和疟疾 (5.6%) 是确定的感染.
- 过去的捐赠经验,静脉注射药物使用和危险的性行为与TRI风险增加有关 (p < 0.05).
- 与首次捐献者相比,重复捐献者的TRI风险略高 (p=0.04).
- 乙型肝炎和艾滋病毒是TRI的独立风险因素.
结论:
- 捐赠者病史,包括以前的捐赠记录和高风险行为,对于预防TRI至关重要.
- 针对性查和基于已识别的风险因素的供体选择可以提高血液安全.
- 对特定的风险行为进行进一步的研究是有必要的,以改进预防策略.
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