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线相关的生物标志物和巨参与肺动脉高血压:识别和功能影响

Xiaoyu Zhang1, Liming Cheng2, Jiahui Xie1

  • 1Department of Cardiac Surgery, Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences/Affiliated Cardiovascular Hospital of Kunming Medical University, Kunming, Yunnan, China.

Frontiers in physiology
|November 21, 2025
PubMed
概括

缺陷的线粒细胞吸收有助于肺动脉高血压 (PAH). 研究人员确定了五种与巨细胞相关的生物标志物 (RRAS,BECN1,MFN1,HIF1A,TAX1BP1),具有对PAH的高诊断潜力.

关键词:
生物标志物 生物标志物巨细胞是什么?巨细胞是什么?线粒细胞衰变 (mitophagy) 是一种神经衰变的过程.肺动脉高血压 肺动脉高血压一个单细胞RNA测序.

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Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
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