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Updated: Jan 10, 2026

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
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PC/BCP突变对HBeAg阳性慢性乙型肝炎患者血清转化和复发的影响,这些患者接受了核酸类类似物治疗

Shulin Xia1, Xiaomin He1, Jianhe Gan2

  • 1Department of Infectious Diseases, The Taixing People's Hospital, Taixing City, Taizhou, Jiangsu, 225400, People's Republic of China.

Infection and drug resistance
|November 21, 2025
PubMed
概括

在乙型肝炎病毒 (HBV) 中的前核/基核促成因子 (PC/BCP) 突变显著降低了血清转化率,并增加了使用核类相应物 (NA) 治疗的慢性乙型肝炎 (CHB) 患者的复发率. 建议对个性化NA疗法进行这些突变的常规测试.

关键词:
乙型肝炎病毒的感染.在PC/BCP突变中.核子是同类的同类物质.这是一个复发的复发.血清转换是一种血清转换.

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