电子烟对呼吸系统健康的影响的最新证据:系统性审查和元分析
Anasua Kundu1, Anna Feore2, Nada Abu-Zarour3
1Institute of Medical Science, University of Toronto, Toronto, Canada.
Tobacco induced diseases
|November 21, 2025
概括
尼古丁电子烟的使用与呼吸系统问题有关. 与从未吸烟者相比,吸烟增加了非吸烟者患呼吸道症状和慢性阻塞性肺病 (COPD) 的风险.
科学领域:
- 呼吸系统健康 呼吸系统健康
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 尼古丁电子烟 (vaping) 产品的使用在全球普遍存在.
- 人们对电子烟对呼吸系统健康的影响存在担忧.
- 本综述综合了关于电子烟和呼吸系统结果的当前证据.
研究的目的:
- 评估电子烟使用与呼吸系统健康之间的关联.
- 分析呼吸道症状,慢性阻塞性肺病 (COPD),喘和肺炎的风险.
- 为了比较不同用户群体的风险:从未使用者,电子烟者,吸烟者和双重使用者.
主要方法:
- 从2023年1月开始,对主要数据库 (CINAHL,Embase,MEDLINE,PsycINFO,PubMed,Cochrane) 的系统文献搜索,更新至2024年1月.
- 包括同行评审的人类,动物和体外试验研究 (2021年7月至2023年12月),不包括定性研究.
- 对三种暴露类型的分析:急性,短期到中期和长期的电子烟使用.
主要成果:
- 与从未使用电子烟的人相比,非吸烟者表现出更高的呼吸道症状风险 (RR=1.90).
- 与从未使用者相比,双重使用者表现出呼吸系统症状 (RR=2.53) 和COPD患病率 (RR=3.86) 的风险增加.
- 适度的证据表明,非吸烟者对非吸烟者的呼吸道症状,COPD,喘和肺炎的风险更高.
结论:
- 电子烟的使用与不良的呼吸系统影响有关.
- 有证据表明,电子烟有助于呼吸系统症状发生率和COPD.
- 需要进一步的纵向研究来澄清电子烟在不同用户群体的长期呼吸系统影响.
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