白人参对通过增强默认模式网络连接来减轻压力和紧张的作用:一项随机,双盲,安慰剂控制的临床试验
Youngeun Shim1,2, Young-Seob Lee3, Yejin Kim1,2
1Ewha Brain Institute, Ewha Womans University, Seoul, 03760, Republic of Korea.
Journal of ginseng research
|November 21, 2025
概括
白人参 (Panax ginseng Meyer,PGC) 在12周的试验中显著降低了压力和紧张. 通过调节大脑连接,PGC可以缓解心理状况,在压力管理方面显示出有希望的结果.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 对白人参 (Panax ginseng Meyer, PGC) 对心理健康的兴趣日益增长.
- 目前正在调查PGC在减轻压力和紧张的潜在作用.
研究的目的:
- 为了评估PGC在12周内减少压力和紧张的有效性和安全性.
- 探索PGC对大脑功能连接的影响.
主要方法:
- 随机,双盲,安慰剂对照试验,共86名参与者.
- 通过复合压力指数 (自我报告,皮肤导电性,心率变化) 评估压力.
- 休息状态功能性MRI用于分析大脑连接.
主要成果:
- 与安慰剂相比,PGC显著降低了复合压力指数 (P=0.006).
- PGC组显示,默认模式网络 (DMN) 功能连接的减少更大 (P=0.002).
- 减少的DMN连接与PGC组中较低的压力水平相关 (r=0.410,P=0.025).
结论:
- PGC显示出减轻压力和紧张的潜力.
- 调节DMN功能连接可能是PGC减压效应的基础.
- PGC耐受性很好,没有显著的不良事件或学.
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