在患有左心房附属塞装置的患者中,心房动的直流心转
Xin Xie1, Zijun Chen1, Xiaorong Li1
1Department of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Frontiers in cardiovascular medicine
|November 21, 2025
概括
在患有左心房尾闭塞 (LAAO) 装置的患者中,直流心脏转换 (DCCV) 是安全有效的. 这项研究发现,在LAAO装置植入后接受DCCV的患者中,不良事件或血栓塞栓的风险没有增加.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 关于对患有左心房尾闭塞 (LAAO) 装置的患者使用直流心脏转换 (DCCV) 的安全性和疗效的数据有限.
- 了解DCCV对该群体血栓栓塞预防的影响对于临床决策至关重要.
研究的目的:
- 调查DCCV的安全性和有效性在经过LAAO手术的患者中.
- 评估与DCCV相关的风险及其对LAAO设备患者血栓栓塞事件的影响.
主要方法:
- 一项雄心勃勃的队列研究包括196名接受LAAO的患者,其中95人接受了DCCV后期治疗.
- 安全终点包括与DCCV相关的死亡,设备脱离/栓塞以及严重出血.
- 疗效终点包括全因死亡,心血管死亡,中风/暂时性缺血性发作和全身栓塞.
主要成果:
- 没有发生与DCCV相关的死亡,设备脱离或栓塞.
- 安全性终点 (3.2%对6.9%) 和疗效终点 (1.1%对4.0%) 在12个月后在DCCV和非DCCV组之间没有显著差异.
- 经食道心声扫描显示DCCV后设备直径的轻微,非有害变化.
结论:
- 在患有左心房尾闭塞 (LAAO) 装置的患者中,可以安全地进行直流心脏转换 (DCCV).
- 没有观察到增加不良事件或血栓栓塞并发症的风险.
- 在TEE上观察到的轻微设备直径变化与不良结果无关.
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