针对代谢功能障碍相关的脂肪肝疾病的基于运动的干预措施:系统性审查和元分析的总体审查
Xinjuan Huang1, Ruoling Yu1, Manjie Guo1
1Xiangya School of Nursing, Central South University, and Department of Nursing, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, China.
Nutrition reviews
|November 21, 2025
概括
每周4-5次以中等至高强度的运动,结合有氧和抵抗训练,最能改善代谢功能障碍相关脂肪肝病 (MAFLD) 患者的脂质概况. 较长时间坚持30-60分钟的会话会产生更好的结果.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 运动生理学 运动生理学
- 公共卫生 公共卫生
背景情况:
- 与代谢功能障碍相关的脂肪肝疾病 (MAFLD) 的患病率在全球范围内正在上升.
- 运动是关键的治疗方法,但最佳的治疗方案尚未确定.
- 这项研究综合了对MAFLD运动处方的证据.
研究的目的:
- 系统地审查和综合有关MAFLD运动处方 (频率,强度,持续时间,类型) 的证据.
- 评估现有系统审查的方法质量和证据水平.
- 为MAFLD管理提供基于证据的建议.
主要方法:
- 在6个数据库 (PubMed,Embase等) 中进行系统搜索. 在2024年4月之前进行系统审查和元分析.
- 使用AMSTAR-2和GRADE评估的运动处方变量和结果的数据提取.
- 包括来自506项已识别的研究的23项系统性审查,并进行了逆向引用跟踪.
主要成果:
- 最佳的运动频率:每周2-5次 (最佳的脂质改善为4-5次).
- 推强度:中度至高度;持续时间:每次30-60分钟.
- 建议结合有氧和抵抗训练;较长时间的坚持改善了结果.
- 82%的研究质量低至非常低;整体证据质量低至中等.
结论:
- MAFLD患者从每周4-5次中度至高强度运动中获益,特别是为了改善脂质状况.
- 在可行的情况下,建议将有氧和抵抗运动结合起来.
- 坚持30-60分钟的会议是最优的,更长的持续时间可能会增加益处.
- 需要进一步进行高质量的研究,以完善运动处方和进行剂量反应分析.
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