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Updated: Jan 10, 2026

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与ABCA4相关的视网膜病变中的内视网膜变化:结构功能关系

Andrea Maria Coppé1, Giancarlo Iarossi1, Alessandro Cappelli1

  • 1Ophthalmology Department, Bambino Gesù Children's Hospital, Palidoro (Rome), Italy.

Investigative ophthalmology & visual science
|November 21, 2025
PubMed
概括

与ABCA4相关的视网膜发育不良 (ABCA4-RD) 显示内视网膜变薄和减少光学负反应 (PhNR) 功能. 内视网膜解剖与PhNR振幅相关,这表明ABCA4-RD进展中存在因果关系.

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The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
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