设备感染成像用-18二氧化葡萄糖正子发射断层扫描/计算机断层扫描在患者的左心室辅助装置
Yiğithan Okar1, Reyhan Köroğlu1, Akın Torun2
1Department of Nuclear Medicine, Sultan II. Abdulhamid Han Training and Research Hospital, Istanbul, Türkiye.
-18 FDG PET/CT有效地检测和定位左心室辅助器件 (LVAD) 的患者的感染. 这种成像有助于指导LVAD感染的治疗,改善患者管理.
科学领域:
- 心脏病学 心脏病学
- 核医学是一种核医学.
- 传染性疾病 传染性疾病
背景情况:
- 左心室辅助器件 (LVADs) 改善了晚期心力衰竭的生存率.
- 感染性并发症,包括败血症,在LVAD患者中很常见 (1-2年内20-40%) 并具有挑战性.
- 精确的感染检测和局部化对于有效的治疗至关重要.
研究的目的:
- 评估-18 (F18) 氧葡萄糖 (FDG) 定子发射断层扫描/计算机断层扫描 (PET/CT) 在诊断和定位疑似感染的LVAD患者中的实用性.
- 将PET/CT发现与微生物培养结果进行比较.
主要方法:
- 对15名疑似LVAD感染的患者的F18 FDG PET/CT扫描进行了回顾性分析.
- 评估感染的存在,局部 (驱动线与) 和程度.
- 影像检测结果与微生物培养数据的比较.
主要成果:
- F18 FDG PET/CT显示100%的灵敏度和100%的LVAD感染的负预测值.
- 87%的患者 (13/15) 呈阳性PET/CT检测结果,表明感染.
- 感染局部在10名患者的驱动线上,在3名患者的和驱动线上.
- PET/CT结果与培养发现相关,识别了金黄色葡萄球菌和Pseudomonas aeruginosa.
结论:
- F18 FDG PET/CT是一种高度敏感的,非侵入性的工具,用于检测和定位LVAD感染.
- 这种模式有助于优化治疗策略,可能避免侵入性手术.
- 及时干预,包括考虑心脏移植,得到了PET/CT在感染的研究结果的支持.
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