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了解在固体器官移植中失败的救援:一个范围审查

Jiro Kimura¹, Ayham Asassfeh¹, Emily Cooper²

¹Division of Transplant Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

Clinical transplantation

|November 21, 2025

概括

在固体器官移植 (SOT) 中,救援失败 (FTR) 尚未得到充分理解. 这次审查突出了FTR的重点.

科学领域:

移植医学移植医学
医疗保健服务研究医疗服务研究
关键的护理关键的护理

背景情况:

在固体器官移植 (SOT) 中失败救援 (FTR) 的作用需要进一步阐明.
现有的SOT中FTR研究有限,缺乏标准化.

研究的目的:

进行范围审查,评估与SOT中FTR相关的发病率,并发症和风险因素.
综合不同SOT类型的FTR现有证据.

主要方法:

在PubMed,Scopus和Web of Science中进行系统的文献搜索.
由于研究异质性,提取的数据的叙述综合.
专注于在肝,肺和心脏移植中报告FTR的研究.

主要成果:

七项研究符合纳入标准;没有一项研究专注于脏或胰腺移植.
FTR的定义差异很大,影响了报告的发病率 (肝脏为4.6%至39.6%,肺部为19%至26%,心脏为11.5%).
需要透析的急性损伤 (AKI) 是导致死亡的常见途径;患者,捐赠者和系统因素影响了FTR风险,西班牙裔心脏移植接受者的几率更高.

结论:

在移植中对FTR的证据稀疏且异质.
患者的脆弱性和医疗保健系统的能力是救援结果的关键决定因素.
标准化定义和更广泛的研究包含 (脏,胰腺) 对于开发FTR作为质量指标至关重要.

关键词:

并发症可能导致并发症.没有进行救援.死亡率死亡率质量指标质量指标实体器官移植移植实体器官移植

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