皮肤穿透核心活检在预测脏瘤病理学方面的表现:系统性审查
Rebecca Stokes1, Derek Hennessey1,2, Ned Kinnear3,4
1University College Cork, Cork, Ireland.
BJU international
|November 21, 2025
概括
脏瘤核心活检在检测具有局部脏质量的成年人的恶性瘤方面表现出高准确性. 这种诊断工具具有高度的灵敏度和特异性,有助于治疗决策,并可能减少不必要的手术.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 诊断的准确性 诊断的准确性
背景情况:
- 对局部质的准确诊断对于适当的患者管理至关重要.
- 瘤核心活检是关键的诊断方式,但它的准确性需要系统的评估.
研究的目的:
- 系统地评估脏瘤核心活检的诊断准确性,以检测具有局部脏质量的成年人的恶性瘤.
主要方法:
- 在多个数据库和灰色文献中进行了全面的搜索,直到2024年9月.
- 包括的研究是局部瘤成年患者的非随机队列,使用手术组织学作为参考标准.
- 主要结局是活检敏感度和针对恶性瘤检测的特异性.
主要成果:
- 分析了包括1735名患者在内的21个队列.
- 脏瘤核心活检在检测恶性瘤方面获得了98%的加权平均灵敏度和94%的特异性.
- 在0.97的曲线下面的面积表明了高的测试准确性,尽管偏差风险中等至高.
结论:
- 在患有局部质的成年人中,脏瘤核心活检具有高灵敏度和特异性.
- 常规使用,在切除了活检不会改变管理的情况之后,可能会降低良性瘤的瘤切除率,并提高手术室的效率.
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