与血压相关的临床参数在患有初级开角青光眼和脱皮青光眼的患者
Ayumu Akagi1, Kaito Narimoto1, Kanta Ueda1
1Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, 610- 0394, Japan.
概括
与初级开角青光眼 (POAG) 患者相比,脱皮青光眼 (EXG) 患者的血压 (BP) 形状与初级开角青光眼 (POAG) 患者不同,特别是在年轻人中. 这些差异可能表明潜在的血管问题,并突出显示青光眼亚型和年龄对血压的影响.
科学领域:
- 眼科医生 眼科 眼科
- 心血管健康 心血管健康
- 医疗信息学 医疗信息学
背景情况:
- 血压 (BP) 的特征在不同青光眼亚型之间有所不同,但缺乏详细的比较.
- 了解这些差异对于全面的患者管理至关重要.
研究的目的:
- 通过使用电子医疗记录 (EMR) 调查血压参数和青光眼亚型之间的关系.
- 为了分析初级开角青光眼 (POAG) 和脱皮青光眼 (EXG) 患者之间的BP差异.
主要方法:
- 追溯分析了来自920名青光眼患者的12,322次访问 (POAG和EXG).
- 使用基于变压器的双向编码器表示 (BERT) 的自然语言处理模型进行自动EMR数据提取.
- 进行多变量和年龄分层分析以确定关联和差异.
主要成果:
- 系统性血压与年龄,脉率,眼内压力 (IOP),手术史和药物相关.
- 透支血压与性别,脉率,内血压,青光眼的类型,手术史和药物相关.
- 与POAG患者 (分别为79.6,141.2和60.7 mmHg) 相比,EXG患者的透析血压 (77.9 mmHg) 较低,静脉血压 (146.6 mmHg) 和脉冲压 (68.8 mmHg) 较高.
- 血压差异在60岁以下的患者中最为明显,随着年龄的增长而减少.
结论:
- EXG患者表现出明显的血压概况,可能与脱皮综合征的全身表现和潜在的血管病理有关.
- 青光眼的亚型和年龄都显著影响了青光眼患者的血压概况.
- 基于BERT的EMR分析对于发现临床相关的患者数据和关联是有效的.
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