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相关概念视频

Olfaction01:25

Olfaction

48.0K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
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Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

11.1K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
11.1K
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

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Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
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Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
752
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

1.6K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
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Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

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Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
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相关实验视频

Updated: Jan 10, 2026

A Free-breathing fMRI Method to Study Human Olfactory Function
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A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

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嗅觉功能障碍和认知衰退:它们是否相关?

Concepció Marin1,2, Isam Alobid3,4,5, Mauricio López-Chacón3,4,5

  • 1INGENIO, Multidisciplinary and Translational Research in Inflammation and Immunoallergy (METRI 2 A), Fundació Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Catalonia, Spain. cmarin@recerca.clinic.cat.

Current allergy and asthma reports
|November 21, 2025
PubMed
概括
此摘要是机器生成的。

嗅觉丧失或嗅觉功能障碍与认知能力下降有关. 嗅觉识别障碍可能预测从正常衰老到痴呆的进展,特别是在炎症性呼吸道疾病中.

关键词:
在 COVID-19 疫情中,慢性鼻炎是什么意思 慢性鼻炎认知 认知是一种认知.神经新生是神经发生的过程.嗅觉是一种嗅觉.嗅觉培训 嗅觉培训 嗅觉培训

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Olfactory Assays for Mouse Models of Neurodegenerative Disease
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Olfactory Assays for Mouse Models of Neurodegenerative Disease

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Simple and Computer-assisted Olfactory Testing for Mice
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Simple and Computer-assisted Olfactory Testing for Mice

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相关实验视频

Last Updated: Jan 10, 2026

A Free-breathing fMRI Method to Study Human Olfactory Function
10:42

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

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Olfactory Assays for Mouse Models of Neurodegenerative Disease
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Olfactory Assays for Mouse Models of Neurodegenerative Disease

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科学领域:

  • 神经科学是一个神经科学.
  • 眼科医生 眼科 眼科
  • 衰老研究研究 衰老研究

背景情况:

  • 嗅觉功能与认知健康密切相关.
  • 嗅觉丧失的严重程度与认知能力下降的速度相关.

研究的目的:

  • 审查嗅觉功能障碍和认知能力下降之间的关系.
  • 专注于2型和非2型炎症上呼吸道疾病的相关性.
  • 要突出改变的嗅觉组件和认知衰退进展到痴呆症之间的相关性.

主要方法:

  • 对检查嗅觉功能和认知衰退的研究进行文献综述.
  • 分析嗅觉功能障碍与上呼吸道炎症性疾病之间的关联.
  • 检查特定的嗅觉变化 (例如,气味识别) 与认知进展之间的联系.

主要成果:

  • 嗅觉识别障碍是认知衰退进展的潜在预测因素.
  • 这种进展可以从正常的衰老到轻微的认知障碍和痴呆症.
  • 在2型和非2型炎症上呼吸道疾病的背景下,这种关联很重要.

结论:

  • 嗅觉功能障碍,特别是嗅觉识别障碍,与认知能力下降有显著的关联.
  • 这一联系对于理解衰老和疾病中的神经退行过程具有重要意义.
  • 对嗅觉功能障碍的进一步研究可能会为认知障碍的早期发现和管理提供见解.