多基因组确定了LAB发酵的山羊奶的营养改善
Liyan Ge1, Hengrui Li1, Qiwen Hong1
1Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, P.R. China.
Journal of agricultural and food chemistry
|November 21, 2025
概括
使用乳酸细菌 (LAB) 发酵的山羊奶 (FGM) 改变了其营养特征,增加了有益的化合物和特定的微生物. 这项研究澄清了LAB.
科学领域:
- 微生物学 微生物学
- 营养科学 营养科学
- 生物化学 生物化学
背景情况:
- 发酵山羊奶 (FGM) 的成分受到乳酸细菌 (LAB) 的影响.
- 对于LAB发酵对山羊奶的具体营养影响尚不清楚.
- 了解这些变化对于优化发酵乳制品至关重要.
研究的目的:
- 为了全面分析由LAB引起的FGM多组变化.
- 为了识别在FGM发酵过程中改变的特定代谢物,蛋白质和.
- 阐明在FGM中微生物转移和代谢途径之间的关系.
主要方法:
- 多omics方法包括代谢学,蛋白学和学.
- 微生物分析,以评估细菌种群的变化.
- 相关性和基因和基因组的京都百科全书 (KEGG) 路径分析.
主要成果:
- 减少了FGM中的微生物多样性,增加了Streptococcus和Lactobacillus,并减少了Klebsiella.
- 鉴定了364种代谢物 (59种差异) 和334种蛋白 (20种差异).
- 发现一种具有抗炎性质的FGM特异性,减少TNF-α.
结论:
- 拉布显著提高了山羊奶的营养特征.
- 特定的代谢途径,如TCA循环和pyruvate代谢是由LAB.调节的.
- 这项研究提供了关于LAB在发酵乳制品中的功能益处的见解.
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