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Updated: Jan 10, 2026

Prostate Organoid Cultures as Tools to Translate Genotypes and Mutational Profiles to Pharmacological Responses
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Published on: October 24, 2019

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雄激素受体驱动聚胺合成,为前列腺癌造成脆弱性

Rajendra Kumar1, Sheila Jonnatan2, David E Sanin3

  • 1Johns Hopkins Medicine, Baltimore, Maryland, United States.

Cancer research
|November 21, 2025
PubMed
概括

超生理性雄激素 (SPA) 在前列腺癌中促进聚胺合成,促进瘤生长. 抑制聚胺的产生增强了SPA的疗效,揭示了双极雄激素疗法 (BAT) 的治疗脆弱性.

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