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对大血管闭合性中风机械血栓切除术后侧向循环对中风后的影响:一个多中心队列研究
Peng Jiang1, Zongzhi Jiang2, He Sui2
1Department of Neurology, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, China.
European journal of neurology
|November 21, 2025
概括
缺少附带血液循环显著增加了急性缺血性中风 (AIS) 患者的中风后 (PSE) 的风险,这些患者接受了机械血栓切除术 (MT). 这一发现有助于识别患PSE高风险个体.
科学领域:
- 神经学 神经学
- 心血管医学 心血管医学
- 神经外科 神经外科
背景情况:
- 急性缺血性中风 (AIS) 是成年人获得性的主要原因.
- 在机械血栓切除术 (MT) 后,对中风后 (PSE) 的预测因素尚未得到充分确立.
- 在MT之后,抵押品流通在PSE风险中的作用需要进一步调查.
研究的目的:
- 为了评估贫困的附带循环和在接受MT的AIS患者中发展PSE的风险之间的关联.
- 在这个患者群体中确定PSE的潜在预测因子.
主要方法:
- 在2017-2022年期间接受MT的AIS患者的多中心队列研究.
- 使用调整后的考克斯比例危险模型来评估PSE风险.
- 包括子组,敏感性和竞争风险分析.
主要成果:
- 包括1167名患者 (平均年龄62岁,46.5%为女性).
- 在不良担保流通组 (13.0%) 与对照组 (4.2%) 观察到更高的PSE频率.
- 与充足的抵押品状况 (ASITN/SIR ≥ 2) 相比,不充分的抵押品流通 (ASITN/SIR < 2) 显著增加了12个月和60个月的PSE风险 (HR > 1,p < 0.05).
结论:
- 缺少附带循环是急性缺血性中风机械血栓切除术后发展中风后的重要危险因素.
- 评估附带循环可能有助于识别PSE风险较高的AIS患者.
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