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Updated: Jan 10, 2026

Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology
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对抗表观遗传控制的PAF/PAF-R通路在实验性肝硬化期间改善肝功能

Enrique Ángel-Gomis1, Esther Caparrós2, Isabel Gómez-Hurtado3

  • 1Hepatic and Intestinal Immunobiology Group, Dpto. Medicina Clínica and Instituto IDIBE, Universidad Miguel Hernández, San Juan de Alicante, Spain; IIS ISABIAL, Hospital General Universitario Dr. Balmis, Alicante, Spain.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|November 21, 2025
PubMed
概括

血小板激活因子受体 (PAF-R) 在肝硬化中过度表达,导致肝炎. 与BN-52021对抗PAF-R通过阻断促炎信号通路来改善肝损伤.

关键词:
肝硬化是肝硬化的一种疾病.通过DNA甲基化.肝脏的巨细胞.炎症 炎症是一种炎症.血小板激活因子受体受体

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