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Updated: Jan 10, 2026

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders
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双标CGRP抗剂/5HT1F激动剂治疗偏头痛的结构导向合理设计

Fangxia Zou1, Yutong Mao2, Chunmei Li1

  • 1School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, China.

European journal of medicinal chemistry
|November 21, 2025
PubMed
概括

研究人员开发了一种双重向的偏头痛药物,该药物阻断素基因相关 (CGRP) 并激活血清素5-HT1F受体. 这种策略提供了强大的,外围作用的偏头痛缓解,中枢神经系统的副作用较少.

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