肠道微生物群的个体间变异性介导了对MASLD耐药粉的疗效

Xiaoxue Long1, Hui Wang2, Yuwei Lu1

  • 1State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Shanghai Key Laboratory of Diabetes Mellitus, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China; Department of Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Cell metabolism
|November 21, 2025
PubMed
概括

耐药粉 (RS) 对代谢功能障碍相关的脂肪性肝病 (MASLD) 有好处,但肠道细菌影响其有效性. 像Prevotella这样的特定细菌减少了益处,而Bifidobacterium可以恢复它们,从而实现个性化的MASLD治疗.