抵抗训练改善了血液动力学,涉及自主和免疫反应
Eduarda Teodora Rachid-Wolpp1, Boris Brill2, Anamei Silva Reis3
1Laboratory of Pulmonary and Exercise Immunology (LABPEI), UniEVANGELICA University Centre of Anapolis, Anapolis, Brazil.
抵抗训练显著改善了老年人的心血管,自主和免疫功能. 这项为期12周的干预措施提高了身体能力,减少了炎症标志物,这表明它是一种有效的策略来应对与年龄相关的衰退.
科学领域:
- 老年学是一门学科.
- 运动生理学 运动生理学
- 心血管健康 心血管健康
背景情况:
- 衰老与心血管,自主和免疫系统功能的显著损害有关.
- 抵抗训练对抗老年人与年龄相关的功能衰退的潜力在很大程度上仍未被探索.
研究的目的:
- 为了研究12周耐力训练计划对心血管血液动力学,自主功能和老年人免疫反应的影响.
- 测试抵抗训练可以减轻这些生理系统中与年龄相关的损伤的假设.
主要方法:
- 68名老年人被随机分配到抵抗训练组 (n=31) 或对照组 (n=38).
- 训练组每周三次进行12周的中等强度阻力运动 (最大1次重复的65%-80%).
- 评估包括阻抗心脏图,心电图,坐立测试与SpO2监测,呼吸压力和血细胞因子分析.
主要成果:
- 抵抗训练组在中风体积,心脏输出,全身血管阻力,终端透气体积,早期透气功能,pNN50和TRI方面显示出显著的改善.
- 最大呼气和吸气压力,功能能力 (1分钟的坐立测试) 和氧和也得到了增强.
- 抵抗训练导致促炎性细胞因子 (IL-6,TNF-α) 的减少,而抗炎性细胞因子 (IL-10) 和klotho水平的增加.
结论:
- 12周的抵抗训练计划有效地改善了老年人的心血管血液动力学和自主平衡.
- 抵抗运动还可以增强呼吸肌肉的强度,功能能力,并通过减少炎症来调节免疫反应.
- 这些发现强调了抵抗训练是减轻老年人群与年龄相关的生理衰退的有益干预措施.
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