探索献血与贫血之间的关联:基于NHANES的横截面研究
Cong Lv1, Ling Zeng1, Wenhui Zhu2
1Department of Clinical Laboratory, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405 Guangdong, China.
概括
献血与美国成年人缺铁性贫血有关,但与整体贫血无关. 建议进行进一步的研究和供体监测,以确保献血者健康.
科学领域:
- 血液学 血液学 血液学
- 公共卫生 公共卫生
- 营养科学 营养科学
背景情况:
- 献血对公共健康至关重要,但仍存在对捐献者的铁状况的担忧.
- 重复献血会导致缺铁和贫血,影响献血者的健康.
- 关于代表性人口中献血者中贫血和缺铁患病率的数据有限.
研究的目的:
- 研究美国成年人献血与贫血,缺铁和缺铁性贫血 (IDA) 之间的关联.
- 分析国家数据,了解献血对铁的健康影响.
主要方法:
- 从2011-2018年国家健康和营养检查调查 (NHANES) 中对美国成年人 (≥18岁) 的横截面分析.
- 在过去12个月内自报献血.
- 使用血红蛋白,血清铁素,血清铁,TIBC和转激素和评估贫血,缺铁和IDA;采用多变量逻辑回归.
主要成果:
- 在16619名成年人中,4.4%的人报告献血.
- 与非捐赠者相比,捐赠者表现出较低的铁储量 (血清费里,血清铁,转蛋白和) 和较高的总铁结合能力.
- 在捐赠者中,缺铁性贫血的发生率显著增加 (5.7%对1.3%),捐赠与IDA有很强的关联 (aOR 3.72).
结论:
- 献血独立地与美国成年人缺铁性贫血有关.
- 献血和整体贫血之间没有发现显著的关联.
- 加强捐赠者监测和预防策略对于保护捐赠者健康,同时保持血液供应至关重要.
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