评估异步,信息传递,创伤焦点治疗创伤后应激障碍的有效性和参与策略:混合有效性实施随机对照试验的研究设计和方法
Katherine A Dondanville1, Amber Calloway2, Elizabeth C Stade3
1Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at San Antonio, United States of America.
Contemporary clinical trials
|November 21, 2025
概括
这项研究测试了CPT-Text,这是治疗创伤后应激障碍 (PTSD) 的基于文本的疗法,并发现它是有效的. 鼓励参与者"向前付款"的激励措施提高了对这种可访问的PTSD治疗的参与度.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 数字健康数字健康
- 实施科学 实施科学
背景情况:
- 创伤后应激障碍 (PTSD) 对个人和社会构成重大挑战,对像认知处理疗法 (CPT) 这样的有效治疗方法的获取有限.
- 传统PTSD治疗的障碍包括后勤,财务和耻辱相关的问题,需要创新的交付方法.
- 非同步的,由治疗师提供的数字干预提供了一个潜在的解决方案,以改善PTSD护理的获取和参与.
研究的目的:
- 评估CPT-Text的临床有效性和实施可行性,这是CPT对PTSD的一种新型文本消息调整.
- 为了比较CPT-Text与通过安全短信传递的文化知情待遇 (CI-TAU).
- 评估一种促进利他主义的新型参与激励措施 (RAU+I) 对治疗参与和治疗结果的影响.
主要方法:
- 一个混合有效性实施随机对照试验,涉及300名患有PTSD的参与者.
- 随机化为CPT-Text或CI-TAU,以及标准提醒 (RAU) 或基于激励的提醒 (RAU+I).
- 主要结局测量了PTSD症状严重程度 (PCL-5) 和参与度;次要结局包括抑郁症,功能和物质使用. 一个大型的语言模型工具被开发用于忠实度评估.
主要成果:
- 假设CPT-Text与CI-TAU相比,可以显示出优异的PTSD症状减少.
- 预计RAU+I条件将提高治疗参与度和临床结果.
- 探索性分析将调查治疗效应的调节者以及动机在推动变革中的作用.
结论:
- CPT-Text是一个可扩展和可访问的PTSD干预措施,解决传统疗法的局限性.
- 参与激励模式可以提高数字心理健康干预措施的坚持和有效性.
- 结果将指导开发强大的,可访问的技术介导疗法,用于服务不足的人群与PTSD.
相关概念视频
Elements Crucial for Effective Psychotherapy
318
Research has highlighted several critical factors that influence the effectiveness of psychotherapy, such as the therapeutic alliance, the therapist, and the client.
The Therapeutic Alliance
The therapeutic alliance refers to the relationship between the therapist and the client. The alliance strengthens when the therapist and the client engage in a nurturing, supportive, trusting, empathetic, and respectful relationship, improving therapeutic outcomes. Therapists must monitor this relationship...
The Therapeutic Alliance
The therapeutic alliance refers to the relationship between the therapist and the client. The alliance strengthens when the therapist and the client engage in a nurturing, supportive, trusting, empathetic, and respectful relationship, improving therapeutic outcomes. Therapists must monitor this relationship...
318
Interpersonal Psychotherapy
286
Interpersonal psychotherapy (IPT) is a structured, time-limited therapeutic approach initially developed to treat depression. It integrates key concepts from psychodynamic, humanistic, and cognitive-behavioral therapies, making it a uniquely eclectic framework. The therapy is rooted in the interpersonal theories of Adolph Meyer and Harry Stack Sullivan, as well as John Bowlby's attachment theory, and focuses on the interplay between interpersonal relationships and emotional well-being.
286
Modeling in Therapy
366
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
366
Treatment Strategies for Psychological Disorders
672
Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
672


