准则组织的指导文件文件5:利益冲突和资金
Joanne Khabsa1, Zeina Itani2, Hussein A Noureldine3
1Clinical Research Institute, American University of Beirut, Beirut, Lebanon.
Journal of clinical epidemiology
|November 21, 2025
概括
准则组织通常在政策中解决利益冲突 (COI) 和资金,但细节和管理策略各不相同. 政策通常需要利益声明,但缺乏验证和具体的管理标准,这表明在实践指南制定方面有改进的余地.
科学领域:
- 卫生政策 卫生政策
- 医学指导方针 医学指导方针
- 利益冲突管理 利益冲突管理
背景情况:
- 实践指南对于医疗保健决策至关重要.
- 偏见可能来自贡献者利益冲突 (COI) 和资金来源.
- 透明的政策对于减轻指南制定中的偏见至关重要.
研究的目的:
- 检查指南制订组织的政策.
- 描述利益冲突 (COI) 和资金的方法.
- 为了确定政策制定中的变化,为实践准则制定准则.
主要方法:
- 公开可用的指导文件的描述性摘要.
- 关于组织特征,COI政策和资金政策的数据抽象.
- 评估COI政策,包括声明,验证,评估,管理和报告.
主要成果:
- 133个组织中,有110个有COI和/或资金政策.
- 大多数COI政策要求申报利息 (60%),但缺乏验证 (10%).
- 大多数组织接受外部资金 (70%),其中72%报告了减缓策略.
结论:
- 政策通常涉及COI和资金,但存在矛盾.
- 在验证,COI评估的具体标准和管理流程方面存在差距.
- 需要进一步规范政策,以确保公正的实践准则.
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