利科纳米颗粒在 brojlers 的性能,免疫能力,抗氧化剂防御和对 Pasteurella multocida 感染的抵抗力方面提供了有针对性的改进
Marwa I Abd El-Hamid1, Azza S El-Demerdash2, Rania M S El-Malt3
1Department of Microbiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44511, Egypt.
Microbial pathogenesis
|November 21, 2025
概括
饮食中使用的烯纳米颗粒 (lycopene-NPs) 通过减少Pasteurella multocida感染并增强免疫和抗氧化功能,显著改善了 brojler 的健康状况. 这种新的干预措施减轻了疾病的影响,并提高了受挑战的鸟类的整体表现.
科学领域:
- 禽畜科学 禽畜科学 禽畜科学
- 动物营养 动物营养
- 免疫学 免疫学 免疫学
背景情况:
- 由Pasteurella multocida引起的鸟类菌病导致肉的表现差,死亡率高.
- 有效的控制策略对于家禽产业至关重要.
研究的目的:
- 评估饮食中用烯纳米颗粒 (烯-NP) 在改善肉健康和对Pasteurella multocida耐药性的有效性.
- 评估烯-NP对生长,免疫力,抗氧化剂状况和抗病能力的影响.
主要方法:
- 五组肉被食不同水平的柳科-NP (0,50,100,150毫克/公斤).
- 鸟类在28天大时经过实验感染了多药耐药的P. multocida菌株.
- 评估的参数包括细菌殖民,基因表达,生长性能,肺组织学和抗氧化酶水平.
主要成果:
- 饮食中的烯-NP显著降低了P. multocida的殖民化和病毒性基因表达.
- 百合素-NPs改善了受感染肉的生长减缓和肺部损伤.
- 补充剂调节了炎症和抗氧化基因表达,改善了粘膜屏障功能,并增强了抗氧化酶活性.
结论:
- 饮食中烯-NP提供了一种有前途的策略,用于对抗 brojlers中的鸟类病菌.
- 烯-NP增强免疫和抗氧化能力,从而改善健康和表现.
- 150mg/kg的剂量显示出最显著的有益作用.
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