Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

8.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.6K
Adrenergic Antagonists: Chemistry and Classification of ɑ-Receptor Blockers01:17

Adrenergic Antagonists: Chemistry and Classification of ɑ-Receptor Blockers

1.4K
Adrenergic antagonists, or sympatholytics, inhibit adrenoceptor activation driven by catecholamines or agonists. Based on their adrenoceptor specificity, adrenergic blockers can be categorized into two primary groups: α-adrenergic blockers (α-blockers) and β-adrenergic blockers (β-blockers). α-blockers interact with α1 and α2 subtypes of α-adrenoceptors.
Nonselective α-blockers: Nonselective α-blockers contain haloalkylamine or imidazoline...
1.4K
Positron Emission Tomography01:29

Positron Emission Tomography

6.9K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
6.9K
Types of Radioactivity03:23

Types of Radioactivity

19.3K
The most common types of radioactivity are α decay, β decay, γ decay, neutron emission, and electron capture.
Alpha (α) decay is the emission of an α particle from the nucleus. For example, polonium-210 undergoes α decay:
19.3K
Transducer Mechanism: Enzyme-Linked Receptors01:27

Transducer Mechanism: Enzyme-Linked Receptors

3.8K
Enzyme-linked receptors are cell-surface receptors acting as an enzyme or associating with an enzyme intracellularly. They make excellent drug targets. Drugs can bind to the extracellular ligand-binding domain or directly affect their enzymatic domain and alter their activity.
Major types that are helpful drug targets include:
3.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

New Synthetic Strategies Toward DFO*: Enhanced Yield and Purity of a Key Chelator for <sup>89</sup>Zr Chemistry.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Macropa Scaffold Expansion for Actinium-225 Chelation: A Synthetic Strategy, Labeling Kinetics, and Theoretical Calculations.

Inorganic chemistry·2026
Same author

Comparison of two <sup>18</sup>F-fluorinated glycopeptides for PET imaging of the functional liver mass.

EJNMMI radiopharmacy and chemistry·2026
Same author

Advancing towards cancer theragnostic by probing the <sup>225</sup>Ac decay chain with ultra-high-resolution metallic magnetic calorimeter based detectors.

Communications medicine·2026
Same author

Design and Development of an Automated Pipeline for Medical Hyperspectral Image Acquisition, Processing, and Fusion.

Journal of imaging·2026
Same author

Collagen Imaging in Human Intracranial Aneurysms - a Translational Proof-of-Concept Study.

Translational stroke research·2026

相关实验视频

Updated: Jan 10, 2026

Automated Preparation of [68Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment
10:33

Automated Preparation of [68Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment

Published on: April 25, 2025

1.0K

α 发射器标记放射性片用于瘤的向α治疗.

Patrick A Cieslik1, Björn Wängler1,2,3, Carmen Wängler2,4

  • 1Heidelberg University, Medical Faculty Mannheim, Clinic of Radiology and Nuclear Medicine, Molecular Imaging and Radiochemistry, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.

Journal of medicinal chemistry
|November 21, 2025
PubMed
概括

与β-发射体相比,α-发射体放射性提供了优越的瘤治疗方法. 未来的研究必须解决挑战,以充分利用向性α疗法 (TAT) 治疗癌症.

更多相关视频

Preparing a 68Ga-labeled Arginine Glycine Aspartate RGD-peptide for Angiogenesis
07:48

Preparing a 68Ga-labeled Arginine Glycine Aspartate RGD-peptide for Angiogenesis

Published on: January 7, 2019

7.3K
Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
09:44

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Published on: January 29, 2019

10.5K

相关实验视频

Last Updated: Jan 10, 2026

Automated Preparation of [68Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment
10:33

Automated Preparation of [68Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment

Published on: April 25, 2025

1.0K
Preparing a 68Ga-labeled Arginine Glycine Aspartate RGD-peptide for Angiogenesis
07:48

Preparing a 68Ga-labeled Arginine Glycine Aspartate RGD-peptide for Angiogenesis

Published on: January 7, 2019

7.3K
Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
09:44

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Published on: January 29, 2019

10.5K

科学领域:

  • 核医学是一种核医学.
  • 在瘤学瘤学.
  • 放射性药物疗法是一种放射性药物疗法.

背景情况:

  • 类是核医学中用于诊断和治疗的关键瘤定位剂.
  • 从历史上看,贝塔发射体标记是受体特异性癌症治疗的标准.
  • 由于更高的治疗效率,正在出现向α-发射器标记的转变.

研究的目的:

  • 讨论alpha-emitter放射性在瘤向性alpha疗法 (TAT) 中的优势.
  • 识别和突出阻碍阿尔法发射体治疗充分发挥潜力的挑战.

主要方法:

  • 关于放射性类药物治疗的当前文献的审查.
  • 分析阿尔法发射器对β发射器的优势.
  • 识别针对性阿尔法疗法的应用中的挑战.

主要成果:

  • 在瘤治疗中,α发射器的治疗效率明显高于β发射器.
  • 由于其有利的特性,类作为有效的放射性核酸载体.
  • 过渡到α-发射放射性体代表了核医学治疗的重大进步.

结论:

  • 使用α-发射放射性的向性α疗法 (TAT) 在癌症治疗方面显示出很大的前景.
  • 克服当前的挑战对于充分发挥TAT的潜力至关重要.
  • 需要进一步的研究来优化瘤学中的α-发射体放射性的应用.