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Updated: Jul 30, 2026

Use of Single Molecule Fluorescent In Situ Hybridization SM-FISH to Quantify and Localize mRNAs in Murine Oocytes
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多重化smFISH揭示了神经局部化mRNA的空间组织与丰富性有关

Renesa Tarannum1,2, Grace Mun1, Fatima Quddos1,2

  • 1Fralin Biomedical Research Institute at Virginia Tech Carilion, Center for Neurobiology Research, Roanoke, Virginia 24016.

eNeuro
|November 21, 2025
PubMed
概括

神经元中的信使RNA (mRNA) 在RNA颗粒中被运送到突触. 它们在神经中的空间组织主要是由丰富性驱动的,这表明随机相互作用决定了运输效率.

关键词:
在RNA颗粒的RNA颗粒中.在RNP中,RNP的组成是:mRNA局部化的情况.多重成像成像多重成像神经元神经元的神经元

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Regulated mRNA Transport02:22

Regulated mRNA Transport

In eukaryotes, transcription and translation are compartmentalized; an mRNA is first synthesized in the nucleus and then selectively transported to the cytoplasm for protein synthesis. Before transport, a pre-mRNA undergoes several steps of post-transcriptional modifications including splicing, 5' capping, and the addition of a poly-adenine tail. Various proteins bind to the pre-mRNA during these modifications. The mRNA transport takes place with the help of multiple proteins playing specific...