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Updated: Jan 10, 2026

Simple and Fast Rolling Circle Amplification-Based Detection of Topoisomerase 1 Activity in Crude Biological Samples
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Published on: December 2, 2022

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拓糖酶IIb结合将局部突变过程和癌症基因组中的驱动突变划分出来

Liis Uusküla-Reimand1,2, Christian A Lee2,3, Robin H Oh4,5

  • 1Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.

Nature communications
|November 21, 2025
PubMed
概括

拓酶TOP2B通过结合癌症驱动基因和突变区域来维护基因组完整性. 它的活性影响癌症突变,突出其在癌症基因组学中的作用.

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