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Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

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Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
575
CNS Stimulants: Psychedelic Agents01:22

CNS Stimulants: Psychedelic Agents

645
Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
645
Altered States of Awareness01:06

Altered States of Awareness

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Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
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Depth Perception and Spatial Vision01:15

Depth Perception and Spatial Vision

1.8K
Depth perception is the ability to perceive objects three-dimensionally. It relies on two types of cues: binocular and monocular. Binocular cues depend on the combination of images from both eyes and how the eyes work together. Since the eyes are in slightly different positions, each eye captures a slightly different image. This disparity between images, known as binocular disparity, helps the brain interpret depth. When the brain compares these images, it determines the distance to an object.
1.8K
Visual Agnosia01:12

Visual Agnosia

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Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
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Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

8.7K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
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相关实验视频

Updated: Jan 10, 2026

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

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西会改变视觉上下文计算.

Marco Aqil1,2,3, Gilles de Hollander4,5, Nina Vreugdenhil6,7,8

  • 1Spinoza Centre for Neuroimaging, Amsterdam, the Netherlands. m.aqil@spinozacentre.nl.

Nature communications
|November 21, 2025
PubMed
概括
此摘要是机器生成的。

在魔法中发现的一种化合物psilocybin,改变了我们感知上下文的方式,并影响了大脑活动. 这项研究揭示了改变的上下文计算可能是迷幻效应背后的一个关键机制.

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Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior
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How to Find Effects of Stimulus Processing on Event Related Brain Potentials of Close Others when Hyperscanning Partners
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科学领域:

  • 神经科学是一个神经科学.
  • 心理药理学 心理药理学
  • 计算精神病学是一种计算精神病学.

背景情况:

  • 众所周知,psilocybin可以诱导意识和感知的深刻变化.
  • 了解迷幻药作用的神经和计算机制至关重要.

研究的目的:

  • 研究psilocybin对上下文感知和皮层处理的影响.
  • 开发一种计算模型,解释西诱导的视觉感知和神经活动的变化.

主要方法:

  • 心理物理学用埃宾豪斯幻觉来评估感知变化.
  • 超高场功能磁共振成像 (fMRI) 用于测量大脑活动.
  • 计算建模以链接行为和神经发现.

主要成果:

  • 在埃宾豪斯幻觉中,psilocybin显著改变了表现,表明了上下文感知的变化.
  • 对视觉刺激的皮层反应显示在psilocybin.bin下改变了上下文调制.
  • 一个计算模型成功地捕获和整合了观察到的行为和神经效应.

结论:

  • 改变的上下文计算代表了一个潜在的一般机制为psilocybin的效果.
  • 这项研究为通过预测处理的透视来理解迷幻行为提供了一个框架.
  • 视觉作为一个模型系统,以阐明幻觉诱导的认知和神经转变的更广泛原则.