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Updated: Jun 20, 2026

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基准分析信息学工作流程用于数据独立获取单细胞蛋白质组学

Jianwei Wang1, Yi Huang1,2, Fanghua Lu1,2

  • 1Single-Cell Proteomics Research Center, and Zhejiang Key Laboratory of Intelligent Manufacturing for Functional Chemicals, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou, China.

Nature communications
|November 21, 2025
PubMed
概括

本研究引入了一个框架,用于比较单细胞蛋白质组学数据分析策略,使用数据独立采集质谱法 (DIA MS). 它比较软件工具和信息化工作流程,以指导DIA MS数据分析.

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相关概念视频

Overview Of Cell Separation And Isolation01:20

Overview Of Cell Separation And Isolation

Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.