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在老年人中增加基底腺体体积,有耳

Simón San Martin^1,2, Vicente Medel³, Hayo Breinbauer¹

¹Departamento de Neurociencia, Facultad de Medicina, Universidad de Chile, Santiago, Chile.

Scientific reports

|November 21, 2025

概括

与年龄相关的耳声可能涉及大脑基底腺节的变化,而不仅仅是听觉通路. 这项研究发现,耳的老年人基底腺体体积增加,这表明中枢神经系统的作用.

科学领域:

神经科学是一个神经科学.
听觉神经科学听觉神经科学
老年学是一门学科.

背景情况:

耳会影响10%-15%的人口,随着年龄的增长而增加.
传统上被视为听觉,中枢神经系统的参与越来越被认可.
"门假说"涉及耳病理生理学中的前胸腺网络.

研究的目的:

在老年人中研究皮质下大脑结构和听觉功能,这些成年人患有轻度大脑.
检查 tinnitus 患者和对照者之间的基底和听觉通路体积的差异.
澄清皮下灰质在与年龄相关的声中的作用.

主要方法:

结构磁共振成像 (MRI) 用于大脑体积分析.
听觉脑干反应 (ABRs) 用于评估皮质下听觉功能.
51名耳患者和来自ANDES队列的40名年龄匹配对照的比较.

主要成果:

年龄,听力损失,认知障碍或ABR幅度没有显著差异.
耳患者在基底质结构 (条形状,形状) 中显著增加了体积.
在各组之间的听觉区域中没有发现显著的体积差异.

结论:

这些发现支持了基底质在与年龄相关的耳病理生理学中的作用.
表明中枢神经系统的变化,特别是基底,有助于耳.
强调在耳研究中需要考虑超越听觉通路的皮质下结构.

关键词:

衰老的衰老衰老的衰老基底腺节是基底腺节.这就是为什么MRI是MRI.普雷斯比库斯是指一个长老.感官门关闭感官门关闭声 (Tinnitus) 是一种听力障碍.

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