在以人口为基础的分析中,身体活动和抑郁症与开放角眼的独立关联
Sang Yeop Lee1,2, Sang-Jun Shin3, Jeongwoo Lee3
1Department of Ophthalmology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.
Scientific reports
|November 21, 2025
概括
在被诊断为开角玻璃眼 (OAG) 后保持高体力活动 (PA) 显著降低了抑郁症的风险. 诊断后持续高或不断增加的PA在OAG患者中提供了对发展抑郁症的最大保护.
科学领域:
- 眼科医生 眼科 眼科
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 开角玻璃眼 (OAG) 患者面临抑郁症风险增加.
- 身体活动 (PA) 对心理健康有好处,但其在OAG相关抑郁症中的作用尚未得到充分研究.
研究的目的:
- 调查身体活动模式与新诊断OAG的患者中抑郁症发病率之间的关联.
主要方法:
- 使用韩国国家医疗保险服务数据 (2011-2023) 的回顾性队列研究.
- 包括97,617名OAG患者和匹配的对照,分析PA水平 (低/高) 和模式 (一致,增加,减少).
- 使用多变量考克斯回归来评估抑郁风险 (ICD-10代码).
主要成果:
- 高PA后OAG诊断与抑郁症风险降低有关 (HR 0.877).
- 持续高的PA显示出最大的益处 (HR 0.855),其次是增加的PA (HR 0.912).
- 降低或持续低的PA并没有显著降低抑郁症风险.
结论:
- 在OAG诊断后,较高或增加的身体活动与抑郁风险的适度降低有关.
- 促进PA可以是一个有价值的策略,以减轻抑郁症在全面的绿眼的护理.
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